Genuva SS-31 Vail 50mg Lyophilized Powder

Overview
Beast Muscle brings you the next generation of mitochondrial research compounds. The Genuva SS-31 (Elamipretide) is a synthetic tetra-peptide (D-Arg-dimethylTyr-Lys-Phe-NH2) specifically designed to target cardiolipin on the inner mitochondrial membrane. At 50mg in a lyophilized format, this vial provides a concentrated, stable medium for advanced in-vitro and preclinical investigations.

Key Research Applications
Mitochondrial Bioenergetics: Studies on ATP synthesis efficiency and electron transport chain (ETC) integrity.
Oxidative Stress Attenuation: Reduction of reactive oxygen species (ROS) in cardiomyocytes and renal tubule cells.
Aging & Metabolic Research: Investigating reversal of age-related mitochondrial dysfunction.
Neuroprotection: Potential models for Parkinson’s & Alzheimer’s pathology research.

Product Specifications
Molecular Weight: 699.9 g/mol
Purity: >99% by HPLC; <0.5% residual solvents
Appearance: White to off-white lyophilized cake or powder
Bacterial Endotoxins: <1.0 EU/vial
Sterility: Terminal filtration (0.22 µm) & aseptic filling
Storage: -20°C (±5°C) – stable for 24 months

What Makes Genuva SS-31 Unique?
Unlike generic antioxidants, SS-31 is a cardiolipin-binding peptide that normalizes mitochondrial cristae structure without acting as an uncoupler. This specific affinity for damaged membranes makes it superior for ischemia-reperfusion injury models.

Reconstitution Protocol (For Research Only)
Reconstitute 50mg in 5ml of sterile bacteriostatic water or 0.9% NaCl to yield a 10mg/ml concentration. Gently swirl – do not vortex. Use within 7-10 days if kept at 2-8°C post-reconstitution.

Usage Directions
Preparation: Allow the sealed vial to reach room temperature (20-25°C) for 10 minutes before opening to prevent condensation.
Reconstitution: Inject 5mL of sterile diluent (bacteriostatic water or sterile saline) along the vial’s inner glass wall. Do not directly spray onto the lyophilized cake.
Mixing: Gently rotate the vial for 60 seconds until the solution is clear and free of particulates. Do not shake vigorously – peptide degradation may occur.

Dosing in Research Models:
n-vitro cell cultures: 1–10 µM concentration range (titrate as per assay).
Murine models: 1–3 mg/kg body weight via intraperitoneal (IP) injection.

Storage Post-Reconstitution: Aliquot into sterile vials and store at -20°C for up to 3 months. Avoid repeated freeze-thaw cycles (>2 cycles compromises integrity).
Critical Note: For laboratory bench research only. Not for human or veterinary diagnostic use. Beast Muscle disclaims all liability for off-label use.

Warnings & Safety Compliance
Legal Classification in Egypt: This product is a research-grade chemical. Not registered as a medicine or dietary supplement under Egyptian Drug Authority (EDA) regulations. Purchase requires institutional or laboratory verification.
Hazards: May cause eye/skin irritation (H315, H319). Use fume hood, nitrile gloves, and safety goggles.
First Aid: On skin contact – wash with soap/water for 15 minutes. Eye contact – rinse with saline; seek medical advice if redness persists.
Disposal: Autoclave or incinerate as chemical waste per Egyptian Environmental Affairs Agency (EEAA) guidelines. Do not dispose in household waste.
Pregnancy/Reproductive Hazard: R&D studies indicate embryotoxic potential in animal models. Women of childbearing age must avoid inhalation or dermal exposure.

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